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Therapeutic Benefits: Instead of delivering harmful substances, Harlequin delivers beneficial cannabinoids CBD, CBG, CBC, and others that interact with the body's endocannabinoid system to produce genuine therapeutic effects including pain relief, relaxation, and anxiety reduction

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Regarding this association, possible biological mechanisms elucidating the impact of smoking on anxiety include an array of processes, including the dopaminergic system, gamma-aminobutyric acid, hypothalamic-pituitary-adrenal axis, serotonin, and monoamine oxidase 26-28