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Chronic exposure of mice to SHS (90% side stream, 10% mainstream smoke x 2.8 h/day x 7 days/wk x 10.4 mos) induces dark, shrunken cells, hippocampal thinning, and the presence of activated astrocytes and prominent 8-oxoG staining in the prefrontal cortex (PFC) and hippocampus (HIPP) (Raber et al., 2021