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11 Kuhn et al

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Therefore, we speculate that chronic exposure to e-cigarettes with nicotine may cause permanent effects on arterial stiffness in the long term. The stimulant effect of nicotine has little relevance for health However, considering that smoking and even drinking coffee has the same effect on the body, public health experts had pointed out the importance of putting these findings in the right context

2.3 Measures 2.3.1 Substance use risk Participants risk level for SU was assessed using the CRAFFT 2.1 version screening tool (Car, Relax, Alone, Forget, Friends, Trouble) (23)