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A 48-year-old woman presented to the office of an academic dermatologist specializing in contact dermatitis for evaluation of transient and migrating ill-defined erythematous smooth lesions on unexposed areas of the trunk, chest, and neck (Figure 1)

In this way, nicotine and other addictive drugs are positively reinforcing they tap into the normal instrumental learning mechanism which has evolved to ensure that pleasurable or rewarding activities are repeated