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In fact, within 10 to 20 seconds of inhaling nicotine, it successfully crosses the blood-brain barrier (BBB) and binds to the nicotinic acetylcholine receptors (nAChR)

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After these women gave birth, the researchers sampled the umbilical cord blood , which is the same blood that circulates through the fetus in utero, and performed whats referred to as an epigenome-wide association study (EWAS) to search for correlations between blood cotinine levels of the mothers during pregnancy and epigenetic patterns in the babies at birth