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One neural system that appears to be most affected by cocaine originates in a region, located deep within the brain, called the ventral tegmental area (VTA)

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Importantly, prolonged MEL-EV treatment also contributed to the enhanced ability of these SV-HUC recipient cells to engage in anchorage-independent growth consistent with malignant transformation

Clinicians should subsequently use the 5 As tobacco and nicotine cessation strategy, which includes 5 tasks: Ask, Advise, Assess, Assist, and Arrange (Figure 1)