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The belief that cigarette smoking should not be addressed when someone is admitted for alcohol use disorder (AUD) treatment has deep roots in early AA teachings and the addiction treatment culture that followed

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This may contribute the COPD pathology, inducing apoptosis, tissue damage as well as airway inflammation, since airway epithelial cells respond to increased ROS levels by producing cytokines/chemokines that attract inflammatory cells to the area of damage [5, 6, 21, 23, 24]