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In the study, scientists discovered that smokers produce 15 to 20 percent less dopamine in their brains than nonsmokers Related : The Better Man Project From Mens Health 2,000+ Awesome Tips on How to Live Your Healthiest Life Thats partly why cigarettes can be so addicting: When you smoke, the nicotine activates receptors in your brain that release dopamine, which makes you feel a sense of pleasure, according to John Krystal, M.D., editor of Biological Psychiatry and professor at Yale University School of Medicine