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Researchers estimate that 8 million premature smoking-related deaths from any cause were avoided because of a dramatic decline in cigarette smoking rates from the mid-1960s to 2012

This review examines the intricate relationship between cigarette smoking, smoking cessation therapies and anti-TB drugs, focusing on the impact of tobacco smoking compounds on liver detoxifying systems, such as influence of polycyclic aromatic hydrocarbons (PAHs) on hepatic cytochrome P450 (CYP450) enzymes mostly, and on metabolism of antituberculous medications

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