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Macrophages regulate epithelial and stromal cell function by secreting enzymes and inflammatory factors that act directly and indirectly on airway structural cells, such as IL-1, TNF-, IL-8, monocyte chemoattractant protein-1(MCP-1), reactive oxygen species (ROS) and MMPs, directly involved in the process of airway remodelling 60,61

An interesting fact many patients don't know: "Dental abscesses can drain through fistulas, producing a salty taste in the mouth." These small channels allow pus to escape, sometimes providing temporary relief, but the underlying infection remains and requires treatment

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